New York: A team of scientists has identified the corona virus related to SARS-CoV-2 from two bats sampled in Cambodia more than a decade ago.
The discovery, described in the journal Nature Communications, reported that the recent discovery of a known close ancestor of SARS-CoV-2 in cave-dwelling bats in Laos indicated that SARS-CoV-2 related viruses cause the coronavirus. This has a much wider geographic distribution than previously reported and further supports that the pandemic originated through the spillover of a bat-borne virus.
Scientists used metagenomic sequencing to identify nearly identical viruses in two shamel horseshoe bats (Rhinolophus shameli), originally sampled in 2010.
This finding suggested that the SARS-CoV-2 related virus is likely to be spread through several Rhinolophus species.
The authors state that the current geographic distribution of SARS-CoV and SARS-CoV-2 probably reflects a lack of sampling in Southeast Asia or at least in the Greater Mekong subregion, which includes Myanmar, Laos, Thailand, Cambodia and Vietnam, As well as the Yunnan and Guanxi provinces of China.
As with bats, the authors note that pangolins, as well as some species of cat, civet and weasel found in the region, are readily susceptible to SARS-CoV-2 infection and may represent intermediary hosts for transmission to humans. can.
SARS-CoV-2 In 2020, the virus displayed similar strong sequences to SARS-CoV-2 in the receptor binding domain, found in isolated groups of pangolins seized during anti-smuggling operations in southeast China Were.
However, it is not possible to know from where these animals got infected. It is important to note that the natural geographic range of the included pangolin species (Manis javanica) also does not coincide with Southeast Asia and China.
These findings underscore the importance of increased sector-wide investment in bridging capacity for sustainable monitoring of pathogens in wildlife through initiatives such as WildHealthNet, said Lucy Keats of the Wildlife Conservation Society (WCS) Health Program and co-author of the study. Huh.
Continuous and expanded monitoring of bats and other major wild animals in Southeast Asia is essential for the preparation and prevention of future pandemics.
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